Chronic focal polymyositis in the adult

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Chronic focal polymyositis in the adult.

Four patients with chronic focal polymyositis are described. Treatment with steroids appeared to halt clinical progression. The clinical features in all four cases were so strikingly similar as to constitute a syndrome which can be mistaken for muscular dystrophy or spinal muscular atrophy unless investigated fully.

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Cardiac involvement in chronic polymyositis.

This is a report of a 30-year-old male patient with a six-year history of chronic polymyositis. There was no family history of muscular or cardiac disease. Three years after the onset of the illness the patient developed congestive cardiac failure with evidence of complete heart block. Treatment with steroids failed to arrest the course of the disease. Necropsy showed abnormalities in the proxi...

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Fatal myocarditis with acute polymyositis in a young adult.

A 21 year old woman presented with acute polymyositis associated with fatal myocarditis. The significance of cardiac involvement in polymyositis is discussed in relation to this unusually fulminant case.

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Serum KL-6 in adult patients with polymyositis and dermatomyositis.

OBJECTIVE To determine the serum levels of KL-6, a mucin-like high-molecular-weight glycoprotein, in polymyositis/dermatomyositis (PM/DM) patients. METHODS Serum samples from 42 adult PM/DM patients and 38 healthy control subjects were examined using specific enzyme-linked immunosorbent assay (ELISA) systems. RESULTS The serum levels of KL-6 in the PM/DM patients were significantly higher t...

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Rituximab in the treatment of refractory adult and juvenile dermatomyositis and adult polymyositis: a randomized, placebo-phase trial.

OBJECTIVE To assess the safety and efficacy of rituximab in a randomized, double-blind, placebo-phase trial in adult and pediatric myositis patients. METHODS Adults with refractory polymyositis (PM) and adults and children with refractory dermatomyositis (DM) were enrolled. Entry criteria included muscle weakness and ≥2 additional abnormal values on core set measures (CSMs) for adults. Juveni...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1981

ISSN: 0022-3050

DOI: 10.1136/jnnp.44.5.419